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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LGR6 All Species: 2.12
Human Site: S680 Identified Species: 5.83
UniProt: Q9HBX8 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HBX8 NP_001017403.1 967 104298 S680 C V R A Y G K S P S L G S V R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001117499 911 100286 V656 I F A S E S S V F L L T L A A
Dog Lupus familis XP_848875 965 103312 A678 C I R A Y G K A P A L S S V R
Cat Felis silvestris
Mouse Mus musculus Q3UVD5 967 104249 A680 C V R A Y G K A P S P G S V R
Rat Rattus norvegicus Q9Z2H4 951 104120 S656 D L M K H G K S S H L R Q F Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512452 917 101001 I656 Q I T A F L S I F A S E T S I
Chicken Gallus gallus XP_425441 909 100302 A651 L S I F A S E A S I F L L T L
Frog Xenopus laevis NP_001089881 955 105573 H659 D I I K K E K H Q H L R K F Q
Zebra Danio Brachydanio rerio A8WGA3 687 75758 W433 A N S A L I R W P S Q Q H F P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 52.6 89.1 N.A. 90.1 46.5 N.A. 48.5 52.7 45.1 20.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 67.2 92.8 N.A. 93.5 59.8 N.A. 63.8 68.1 59.7 35 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 6.6 73.3 N.A. 86.6 26.6 N.A. 6.6 0 13.3 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 13.3 93.3 N.A. 93.3 46.6 N.A. 33.3 13.3 26.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 12 56 12 0 0 34 0 23 0 0 0 12 12 % A
% Cys: 34 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 23 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 12 12 12 0 0 0 0 12 0 0 0 % E
% Phe: 0 12 0 12 12 0 0 0 23 0 12 0 0 34 0 % F
% Gly: 0 0 0 0 0 45 0 0 0 0 0 23 0 0 0 % G
% His: 0 0 0 0 12 0 0 12 0 23 0 0 12 0 0 % H
% Ile: 12 34 23 0 0 12 0 12 0 12 0 0 0 0 12 % I
% Lys: 0 0 0 23 12 0 56 0 0 0 0 0 12 0 0 % K
% Leu: 12 12 0 0 12 12 0 0 0 12 56 12 23 0 12 % L
% Met: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 45 0 12 0 0 0 12 % P
% Gln: 12 0 0 0 0 0 0 0 12 0 12 12 12 0 23 % Q
% Arg: 0 0 34 0 0 0 12 0 0 0 0 23 0 0 34 % R
% Ser: 0 12 12 12 0 23 23 23 23 34 12 12 34 12 0 % S
% Thr: 0 0 12 0 0 0 0 0 0 0 0 12 12 12 0 % T
% Val: 0 23 0 0 0 0 0 12 0 0 0 0 0 34 0 % V
% Trp: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 34 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _